Saturday, March 20, 2010

John Mayer - Covered In Rain


In these days with the world getting colder
She spends more time sleeping over
Than I planned.

Tonight we're gonna order in
Drinking wine and watching CNN
It's dark I know, but then again
It's the brightest thing I've got.

When I'm covered in the rain, rain
When I'm covered in the rain, rain, rain, rain

From fireworks to fireplaces
Summer stole what fall replaces
And there were people watching all the people
People watching us right back now.

Standing by the missing signs
At the CVS by the checkout line
She puts her crying hands in mine
Cause she's the brightest thing I've got.

When I'm covered in the rain, rain
When I'm covered in the rain, rain, rain, rain
Oh I'm covered in the rain
Oh I'm covered in the rain
Oh I'm covered in the rain
Oh no no oh no no no

And come December Lydia left
She mentions something bout it being for the best
And I can't say I disagree, it's killing me
And now I'm standing facing West
Tracing my fingers around her silhouette
I haven't gotten used to yet
But it's the brightest thing I got.

When I'm covered in the rain, yeah rain
When I'm covered in the rain, rain, rain, rain



Saturday, March 13, 2010

Endorphin The Endogenous Morphine , Sex Hormones and Pheromones




Endorphins are endogenous opioid polypeptide compounds. They are produced by the pituitary gland and the hypothalamus in vertebrates during exercise,[1] excitement, pain, consumption of spicy food and orgasm,[2][3] and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being. Endorphins work as "natural pain relievers."
The term "endorphin" implies a pharmacological activity (analogous to the activity of the corticosteroidendo- and -orphin; these are short forms of the words endogenous and morphine, intended to mean "a morphine-like substance originating from within the body."[4] category of biochemicals) as opposed to a specific chemical formulation. It consists of two parts:
The term endorphin rush has been adopted in popular speech to refer to feelings of exhilaration brought on by pain, danger, or other forms of stress,[1] supposedly due to the influence of endorphins. When a nerve impulse reaches the spinal cord, endorphins are released which prevent nerve cells from releasing more pain signals. Immediately after injury, endorphins allow animals to feel a sense of power and control over themselves that allows them to persist with activity for an extended time.





'Sexercise' yourself into shape


"Sex uses every muscle group, gets the heart and lungs working hard, and burns about 300 calories an hour."
The advice suggests "regular romps this winter" could lead to a better body and a younger look.
Increased production of endorphins "will make your hair shine and your skin smooth," it adds.
"If you're worried about wrinkles - orgasms even help prevent frown lines from deepening."
The article goes on to say that orgasms release "painkillers" into the bloodstream, which helping keep mild illnesses like colds and aches and pains at bay.
The production of extra oestrogen and testosterone hormones "will keep your bones and muscles healthy, leaving you feeling fabulous inside and out".


Sex pheromones

In animals, sex pheromones indicate the availability of the female for breeding. Male animals may also emit pheromones that convey information about their species and genotype.
At the microscopic level, male copepods can follow a three-dimensional pheromone trail left by a swimming female, and male gametes of many animals use a pheromone to help find a female gamete, for fertilization.[14]
Many insect species release sex pheromones to attract a mate, and many lepidopterans (moths and butterflies) can detect a potential mate from as far away as 10 kilometers (6.25 mi). Traps containing pheromones are used by farmers to detect and monitor insect populations in orchards.
Pheromones are also used in the detection of oestrus in sows. Boar pheromones are sprayed into the sty, and those sows which exhibit sexual arousal are known to be currently available for breeding. Sea urchins release pheromones into the surrounding water, sending a chemical message that triggers other urchins in the colony to eject their sex cells simultaneously.

Other pheromones

This classification, based on the effects on behavior, remains artificial. Pheromones fill many additional functions.
  • Nasonov pheromones (worker bees)
  • Royal pheromones (bees)
  • Calming (appeasement) pheromones (mammals)
  • Necromones consisting of Oleic and Linoleic Acids helping animals identify the presence of a dead conspecifics. (Crustaceans and Hexapods)

Uses

[edit] Non-human animals

Pheromones of pest insect species, such as the Japanese beetle and the gypsy moth, can be used to induce many behaviors. As a result, a pheromone trap can be used to trap pests for monitoring purposes, to control the population by creating confusion, to disrupt mating, as well as to prevent further egg laying.
In mammals and reptiles, pheromones may be detected by the vomeronasal organ (VNO), or Jacobson's organ, which lies between the nose and mouth and is the first stage of the accessory olfactory system. Some pheromones in these animals are detected by regular olfactory membranes.

Humans

Few well-controlled scientific studies have ever been published suggesting the possibility of pheromones in humans.
The best known case involves the synchronization of menstrual cycles among women based on unconscious odor cues (the McClintock effect, named after the primary investigator, Martha McClintock, of the University of Chicago).[15][16] This study exposed a group of women to a whiff of perspiration from other women. It was found that it caused their menstrual cycles to speed up or slow down depending on the time in the month the sweat was collected; before, during, or after ovulation. Therefore, this study proposed that there are two types of pheromone involved: "One, produced prior to ovulation, shortens the ovarian cycle; and the second, produced just at ovulation, lengthens the cycle". However, recent studies and reviews of the McClintock methodology have called into question the validity of her results.[17]

The male Axilla (more commonly known as the armpit) has been hypothesized to be a source of human pheromones.
It has been suggested that women with irregular menstrual cycles became regular when exposed to male underarm extracts.[18] They hypothesized that male sweat contains pheromones, which mirror how pheromones affect other mammals.[18]
Other studies have demonstrated that the smell of androstadienone, a chemical component of male sweat, maintains higher levels of cortisol in females,[19] and that the compound is detected via the olfactory mucosa.[20] The scientists suggest that the ability of this compound to influence the endocrine balance of the opposite sex makes it a human pheromonal chemosignal. In 2002, a study showed an unnamed synthetic chemical in women's perfume appeared to increase intimate contact with men. The authors hypothesize, but do not demonstrate, that the observed behavioural differences are olfactorily mediated.[21] This and a previous study by the same authors with the still undisclosed "pheromone" preparation has been heavily criticized for having methodological flaws and that upon re-analyzing there was no effect seen.[22][23]
Other studies have suggested that people might be using odor cues associated with the immune system to select mates who are not closely related to themselves. Using a brain imaging technique, Swedish researchers have shown that homosexual and heterosexual males' brains respond differently to two odors that may be involved in sexual arousal, and that the homosexual men respond in the same way as heterosexual women, though it could not be determined whether this was cause or effect.[citation needed] The study was expanded to include homosexual women; the results were consistent with previous findings meaning that homosexual women were not as responsive to male identified odors, while their response to female cues was similar to that of heterosexual males.[24] According to the researchers, this research suggests a possible role for human pheromones in the biological basis of sexual orientation.[25] In 2008, it was found using functional magnetic resonance imaging that the right orbitofrontal cortex, right fusiform cortex, and right hypothalamus respond to airborne natural human sexual sweat. [26]
In 2006, it was shown that a second mouse receptor sub-class is found in the olfactory epithelium. Called the trace amine-associated receptors (TAAR), some are activated by volatile amines found in mouse urine, including one putative mouse pheromone.[27] Orthologous receptors exist in humans providing, the authors propose, evidence for a mechanism of human pheromone detection.[28]
Some body spray advertisers claim that their products contain human sexual pheromones which act as an aphrodisiac. In the 1970s, "copulins" were patented as products which release human pheromones, based on research on rhesus monkeys.[29] Subsequently, androstenone, axillary sweat, and "vomodors" have been claimed to act as human pheromones.[30] Despite these claims, no pheromonal substance has ever been demonstrated to directly influence human behavior in a peer reviewed study.[29][30][31]